Vitrectomy Combined with Intraoperative Dexamethasone Implant for the Management of Refractory Diabetic Macular Edema

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Dexamethasone intravitreal implant in the treatment of diabetic macular edema

Diabetic macular edema (DME) resembles a chronic, low-grade inflammatory reaction, and is characterized by blood-retinal barrier (BRB) breakdown and retinal capillary leakage. Corticosteroids are of therapeutic benefit because of their anti-inflammatory, antiangiogenic, and BRB-stabilizing properties. Delivery modes include periocular and intravitreal (via pars plana) injection. To offset the s...

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Refractory Diabetic Macular Edema

Diabetic macular edema (DME) is arguably one of the most important challenges in ophthalmology. Macular edema refractory to laser photocoagulation remains the most prevalent cause of untreatable vision loss in diabetes and is responsible for visual disability in millions of people worldwide. The lack of an effective therapeutic solution accounts for the range of interventions proposed. These in...

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Vitrectomy for persistent diffuse diabetic macular edema.

PURPOSE To evaluate the potential benefit of vitrectomy in eyes with persistent diffuse macular edema. DESIGN Prospective randomized comparative clinical trial. METHODS Eyes with diffuse diabetic macular edema for 6 to 18 months, an attached posterior hyaloid, and grid laser photocoagulation performed at least 4 months before were included. Patients were randomized either to a vitrectomy gr...

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Vitrectomy Combined with Intravitreal Triamcinolone Acetonide Injection and Macular Laser Photocoagulation for Nontractional Diabetic Macular Edema

PURPOSE To evaluate the efficacy of vitrectomy combined with intravitreal injection of triamcinolone acetonide (IVTA) and macular laser photocoagulation for the treatment of nontractional diabetic macular edema (DME) refractory to anti-vascular endothelial growth factor (VEGF) therapy. METHODS Twenty-eight eyes from 28 subjects who were diagnosed with nontractional DME refractory to three or ...

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vitrectomy for diffuse refractory diabetic macular edema associated with a taut premacular posterior hyaloid

purpose: to evaluate the anatomic and visual results and complications of vitrectomy in eyes with diffuse refractory diabetic macular edema associated with a taut posterior hyaloid. methods: this prospective interventional case series was conducted on 25 eyes of 22 patients with diffuse clinically significant diabetic macular edema, macular thickness greater than 250 microns on optic coherence ...

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ژورنال

عنوان ژورنال: Korean Journal of Ophthalmology

سال: 2019

ISSN: 1011-8942,2092-9382

DOI: 10.3341/kjo.2018.0100